Sunday, December 29, 2019

What Is the Chemistry Definition of Electrochemistry

Electrochemistry is the scientific study of the chemical species and reactions that take place at the interface between an electron conductor and an ion conductor (electrolyte) in which an electron transfer occurs between the electrode and the electrolyte in solution.

Friday, December 20, 2019

The Roles of HMGA Proteins Essay - 1327 Words

Despite a wealth of biochemical in vitro data on the HMGA proteins of various organisms, their biological role in chromatin is still not convincingly clarified. Current evidence suggests that HMG proteins serve a global role in chromatin by conferring a more â€Å"open† configuration to chromatin regions that are more accessible to transcriptional regulators (Bianchi and Agresti, 2005; Catez et al., 2004). In addition, there is massive evidence that HMGA proteins act as architectural factors that facilitate assembly of functional transcription factor complexes (enhanceosomes) at DNA target sites by various mechanisms. Several studies analysing altered expression levels of HMGA genes in animals have demonstrated that the chromosomal HMGA†¦show more content†¦Therefore, it is the overall aim of my PhD project to gain insight into the in planta functions of HMGA proteins. The project will be performed in the laboratory of Prof. Dr. K.D. Grasser (Regensburg University), w hose research group is specialised on studying plant chromosomal proteins. Towards the goal of elucidating HMGA function, a variety of experimental approaches will be employed using as central tool Arabidopsis plants with altered levels of HMGA protein that will be analysed in comparison to wild type control plants. The available data suggest that HMGA proteins as cofactors assist the proper transcription of putative target genes (Grasser, 2003; Klosterman and Hadwiger, 2002). To evaluate this assumption, (1) we intend to examine plants that have reduced amounts of HMGA (T-DNA insertion mutants, amiRNA plants) as well as plants that have elevated levels of HMGA (overexpression plants). Using these plants we will analyse (2) the consequences of altered HMGA levels on plant phenotype and transcriptome. In addition, (3) the spatial and temporal expression pattern of HMGA is examined as well as (4) protein interactions of HMGA. 3. Work program and Methodology WP1. Starting point of the project is the molecular analysis of Arabidopsis candidate DNA insertion lines (obtained from the NASC stock center) harbouring T-DNA insertions in the gene encoding HMGA. Typically seeds of a segregating population areShow MoreRelatedStructure Based Design And Evaluation Of Synthetic Porphyrin Derivatives Essay1957 Words   |  8 Pagesstop assay. The study indicates that these compounds had strong G-Quadruplex binding affinity with very good inhibitoryactivity in MCF-7 and A549 cell lines. Introduction: DNA has been recognized not only for passive role in genetic-information storage but also an active role in biological processes. In 1953 Watson and Crick proposed a right handed double helix structure of DNA (B-DNA). But it was later found that DNA can adopt other biologically relevant structures too, including the right handed

Thursday, December 12, 2019

Essay on The Book Thief By Markus Zusak Essay Example For Students

Essay on The Book Thief By Markus Zusak Essay To what extent is The Book Thief by Markus Zusak worthy of being deemed ‘Great Literature?’The Book Thief is a relatively recent fictional novel written by Markus Zusak which tells the story of Liesel, a young German girl, and her life throughout the Second World War. Wrought with tragedy, the narrative is told from the point of view of Death, offering a unique insight into human life. Despite how contemporary the novel is, it has received droves of critical acclaim and is often considered to be one of the best books of modern times. But can it be considered ‘great’ literature?There is often debate about what ‘Great’ literature actually is, which is important to consider. For the most part, however, based upon the canon, great literature was originally written by white, Anglo-Saxon males, who are often now dead, as these people were the group who had the political and social power, so in the times when many of the novels were written their view s and experience were considered dominant, so they essentially determined what was ‘great’ literature. However there are many issues with the canon as, although it provides a foundation of what ‘great’ literature actually is, it is widely outdated and is therefore not representative of the rapidly evolving writing styles of present day authors, as well as the habits of readers and the types of novels they enjoy. It becomes even more irrelevant when the fact that ‘great’ literature will not be the same for everyone as different people will have different opinions about whether or not a piece of work can be considered ‘great’ literature.The Book Thief shares a lot of themes with many classic literary novels and indeed those which are relevant to all society. Death is present both in the. .ears it could not be considered ‘great’. Regardless many of its themes are those which are likely to have timeless relevance to society such as war and love, which it also shares with the novels that are generally assumed to be ‘great’ literature, implying that it possesses timeless characteristics as well as the fact that various other aspects suggest that it should be considered ‘great’ literature.I believe that The Book Thief should in fact be considered ‘great’ literature despite its issues concerning how recent it is due to its universal relevance. Furthermore, at this point in time the fact that Zusak does not fit into the canon is almost irrelevant, as the canon is not and should not be a representation of ‘great’ literature in today’s society and is one of the least important factors when considering whether or not a novel should be considered great.